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Petr Maly


Petr Maly

BIOCEV Research Center, Czech Republic

Biography

Petr Maly is the Head of Laboratory of Ligand Engineering at the Institute of Biotechnology, Czech Academy of Sciences in Vestec near Prague, Czech Republic. He has studied at the Department of Biochemistry, Faculty of Science, Charles University in Prague and completed his Doctorate at the Institute of Molecular Genetics, ASCR in Prague. He has completed his Postdoctoral fellowship at the Department of Pathology and Howard Hughes Medical Institute, The University of Michigan Medical School, USA, in the laboratory of Professor John B. Lowe where he has published several substantial papers related to in vivo role of mammalian glycosyltransferases. Since 1998 to 2005 he was a Research Group Leader at the Institute of Molecular Genetics in Prague. He has also worked as Visiting Scientist at the Department of Biochemistry and Molecular Biology of Oklahoma Center for Medical Glycobiology, College of Medicine, the University of Oklahoma, USA. He was a Participating Investigator of Consortium for Functional Glycomics, USA (2001-2008) and Member of Editorial Board (2001-2005) and Editor (since 2003) of the Czech Journal “Biologicke listy”. Since 2008, he has been working on development of combinatorial protein libraries derived from small protein scaffolds and construction of novel high-affinity protein binders with therapeutic and diagnostic potential.

Abstract

Abstract : Targeting IL-23/Th17 pro-inflammatory axis by novel non-immunoglobulin protein binders with an immunosuppressive potential