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Petr Maly,


Petr Maly,

BIOCEV Research Center, Czech Republic

Biography

Petr Maly is head of Laboratory of Ligand Engineering at the Institute of Biotechnology CAS in Vestec, Czech Republic. He studied at Department of Biochemistry, Faculty of Science, Charles University in Prague, Czech Republic (1980-1985) and completed doctorate at the Institute of Molecular Genetics CAS (IMG) in Prague. He spent postdoctoral fellowship (1992-1995) at Department of Pathology and Howard Hughes Medical Institute, The University of Michigan Medical School, Ann Arbor, USA. Since 1998 to 2005 he was a research group leader at the IMG in Prague and also worked at Department of Biochemistry and Molecular Biology, College of Medicine, University of Oklahoma, USA. He also was participating investigator of Consortium for Functional Glycomics (USA, 2001 2008) and Member of Editorial Board (2001-2005) and Editor (since 2003) of the Czech journal “Biologicke listy” (Biological Letters). Since 2008, he has been working on the development of combinatorial protein libraries derived from small protein scaffolds and construction of novel high-affinity protein binders with therapeutic and diagnostic potential.

Abstract

Abstract : Targeting human IL-17 receptor by ABD-derived protein binders as a non-immunoglobulin alternative for modulation of Th-17-dependent pro-inflammatory response