F Kashanian
University of Tehran, Iran
Title: A novel method to effectively remove waste metabolic products
Biography
Biography: F Kashanian
Abstract
The kidney is responsible for regulating acid base balanced and electrolyte concentration example sodium and chloride as well as excreting waste products produced by metabolism like urea and creatinine. It is known that these uremic solutes retention indicating as pathophysiological signs and symptoms lead to kidney insufficiency. In the acute renal failure to protect the health of the patient although dialysis treatment is used to remove mentioned waste products and regulating intracellular fluids but it has some disadvantages. Here introduced Nano Magnetic Bio Polymers Systems (NMBPS) for smart removal of metabolic waste products in blood by means of a kind of absorbents is based on molecular imprinted method. Highly selective separation of metabolites of blood by taking the advantage of applying in the new dialysis device for removing the metabolites is novel and efficient therefore, designing a magnetic capturing mechanism to get rid of all foreign material (magnetic nanoparticles) before return the blood to the patient body is necessary. Prepared NMBPS possessed easy accessibility to the targeted sites and showed fast kinetics, high capacity and favorable selectivity. Successful application of this method in the capturing of the wastes from blood and acceptable recovery after a reasonably mild elution suggested that NMBPS can be used for selectively capturing metabolites in the blood. The benefits of this separation method are capturing the high molecular weight toxins, lower losing the Blood proteins example Albumin and lower long term side effects.